Strain evidence
Lactobacillus acidophilus La-14
Probiotic evidence for vaginal microbiome and pH balance.
- Form
- Live probiotic culture
- Source
- Healthy human
29
Clinical studies
107
Scientific publications
2,037
Clinical participants
Clinically studied benefits
- Intimate health
- Immune health
- Digestive health
- Brain health
Target health outcomes
- Restoration of vaginal microbiota balance (increasing Lactobacillus dominance).
- Reduction in the recurrence of vaginal and urinary tract discomfort.
Recommended population
- Managing vaginal dryness and pH imbalance caused by estrogen decline.
- Postpartum vaginal microbiome restoration and imbalance prevention.
Evidence grade
- Human RCTAvailable
- Meta-analysisAvailable
- ObservationalAvailable
- Animal / in vitroAvailable
Mechanism of action
-
Oral-to-vaginal migration
Survives digestion and migrates to the vaginal tract.
-
Lactic acid production
Lowers local pH to inhibit harmful pathogens.
-
Bacteriocin secretion
Produces natural antimicrobial substances (acidophilin).
-
Result
Maintains a healthy acidic environment and prevents dysbiosis.
Clinical studies
- Randomized controlled trial demonstrates response to a probiotic intervention for metabolic syndrome that may correspond to dietStanford University
- A Healthy Vaginal Microbiota Remains Stable during Oral Probiotic Supplementation: A Randomised Controlled TrialUniversity of Helsinki
- A New Therapy for Uncomplicated Vulvovaginal Candidiasis and Its Impact on Vaginal FloraUniversity of Trieste
- Randomized clinical trial in women with Recurrent Vulvovaginal Candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatmentUniversity of Trieste
- Efficacy of vaginal preparation containing Lactobacillus acidophilus, lactic acid and deodorized garlic extract in treatment and prevention of symptomatic bacterial vaginitis: result from a single-arm pilot studyUniversity of Catania
- Evidence-based mixture containing Lactobacillus strains and lactoferrin to prevent recurrent bacterial vaginosis: a double blind, placebo controlled, randomised clinical trialUniversity of Trieste
- Study on the effects of an oral lactobacilli and lactoferrin complex in women with intermediate vaginal microbiotaUniversity of Trieste
- Lactobacilli vaginal colonisation after oral consumption of Respecta® complex: a randomized controlled pilot studyUniversity of Milan
- The Effect of Synbiotic Supplementation on Uremic Toxins, Oxidative Stress, and Inflammation in Hemodialysis Patients: Results of an Uncontrolled Prospective Single-Arm StudyMedical University of Plovdiv
- Mixture of probiotics reduces inflammatory biomarkers and improves the oxidative/nitrosative profile in people with rheumatoid arthritisState University of Londrina
- Severe allergic rhinitis, perennial sinusitis and antihistamine dependence resolved with naturopathic treatment: A case study and short literature reviewEndeavour College of Natural Health
Real strains. Real studies.
See the formula that uses this strain, and the evidence behind the rest of our strains.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.