Strain evidence
Lacticaseibacillus rhamnosus HN001
Probiotic evidence for women's health and immune balance.
- Form
- Live probiotic culture
- Source
- Cheese
92
Clinical studies
248
Scientific publications
16,113
Clinical participants
Clinically studied benefits
- Intimate health
- Immune health
- Digestive health
- Brain health
- Metabolic health
Target health outcomes
- Improvement in skin barrier function and reduction in allergic skin flare-ups.
- Support for postpartum mental wellness (reduction in anxiety/depression scores).
Recommended population
- Postpartum skin sensitivity (eczema/dermatitis) and emotional well-being support.
- Addressing age-related skin barrier decline and "inflammaging."
Evidence grade
- Human RCTAvailable
- Meta-analysisAvailable
- ObservationalAvailable
- Animal / in vitroAvailable
Mechanism of action
-
Immune Th1/Th2 balance
Shifts immune response to reduce allergic sensitization.
-
Gut-skin axis
Lowers systemic inflammation that triggers skin redness and itching.
-
Neuro-metabolic signaling
Modulates cytokine pathways linked to mood regulation.
-
Result
Clearer skin texture and improved emotional resilience.
Clinical studies
- Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiety: A Randomised Double-blind Placebo-controlled TrialUniversity of Auckland
- Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 yearsUniversity of Otago
- Probiotics for the Prevention of Gestational Diabetes Mellitus in Overweight and Obese Women: Findings From the SPRING Double-Blind Randomized Controlled TrialUniversity of Queensland
- Lactobacilli vaginal colonisation after oral consumption of Respecta® complex (HN001/LA-14)University of Milan
- A Healthy Vaginal Microbiota Remains Stable during Oral Probiotic Supplementation: A Randomised Controlled TrialUniversity of Turku
- Systemic immunity-enhancing effects in healthy subjects following dietary consumption of the lactic acid bacterium Lactobacillus rhamnosus HN001Massey University
- Early pregnancy probiotic supplementation with Lactobacillus rhamnosus HN001 may reduce the prevalence of gestational diabetes mellitus: a randomised controlled trialUniversity of Auckland
- Efficacy of probiotics and lactoferrin in women with Recurrent Vulvovaginal CandidiasisUniversity of Otago
- Microencapsulation of Lactobacillus rhamnosus HN001 by spray drying and its evaluation under gastrointestinal and storage conditionsFederal University of Uberlândia
Real strains. Real studies.
See the formula that uses this strain, and the evidence behind the rest of our strains.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.